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A.G.E. Interrupter Advanced

Our Best Anti-Aging Cream

This next-generation anti-aging cream is formulated with 18% concentrated Proxylane (+20% more activ ... Read full description

A.G.E. Interrupter Advanced

Our Best Anti-Aging Cream

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Skin Type: Dry, Normal, Combination, Sensitive

Skin Concern: Aging, Dullness/Uneven Texture

Features

A.G.E. Interrupter Advanced is a potent corrective cream treatment that helps reverse visible signs of aging impacted by collagen decline and glycation, including wrinkles, laxity, and dullness.

This next-generation anti-aging cream is formulated with 18% concentrated Proxylane (+20% more active than previous A.G.E. Interrupter), 4.25% Wild Fruit Flavonoid blend (+12.5% more active), and new ingredients such as 0.1% Glycyrrhetinic Acid. This advanced technology is clinically shown to reduce the look of five types of wrinkles (forehead wrinkles, glabellar line, crow’s feet, nasolabial folds, and marionette lines), restore the skin's firmness & elasticity, and enhance skin's radiance.

*Due to the formula’s high levels of flavonoids, this cream's color may vary but will remain effective.

Benefits

Helps reduce the look of signs of aging impacted by collagen decline
Reduces the appearance of global fine lines by -14.1% and targeted deep wrinkles by -7.9%
Skin feels firmer
Skin appears more radiant for a healthier-looking complexion
Delivers rich hydration, with a luxurious, satin finish
Free of parabens, drying alcohol, and dyes

CLINICAL STUDY

In a 12-week study, A.G.E. Interrupter Advanced reduced global fine lines by -14.1% and targeted deep wrinkles by -7.9%.

A.G.E. Interrupter Advanced clinically improved attributes associated with skin aging and glycation, including lines and deep wrinkles in multiple facial zones:

+30% skin density
-14% global fine lines
-11.5% forehead wrinkles
-11.2% nasolabial folds
-7.9% marionette wrinkles
-7.3% glabellar wrinkles
-7% crow’s feet

After 12 weeks:

95.9% immediately agree product applies easily
93.2% immediately agree product absorbs quickly
94.7% agree product is suitable for daily use

Twice daily, massage a thin, even layer of A.G.E. Interrupter Advanced wrinkle cream onto the entire face, neck, and chest. If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen. If using with a retinol at night, apply after retinol application.

Collagen and elastin are responsible for skin’s youthful look. While many factors contribute to signs of aging, glycation of these proteins plays a role.

This multi-phase process occurs when excess sugar binds to proteins in skin. Oxidative stressors, like UV, pollution, and diet, expedite the reaction, transforming the bound proteins into A.G.E.s—advanced glycation end-products. A.G.E.s turn flexible proteins brittle, making newly glycated collagen lose its critical regenerative ability. As these degenerated proteins cannot break down to be replaced, skin is ultimately weakened, accelerating signs of visible aging including wrinkles.

A.G.E. Interrupter Advanced is a potent corrective anti-aging cream designed to help reverse visible aging impacted by collagen decline and glycation on the face. This potent anti-aging cream treatment features a high-concentration combination of Proxylane, wild fruit flavonoids, glycyrrhetinic acid, HEPES, and niacinamide to improve visible signs of aging such as wrinkles, laxity, and dullness.

• 18% CONCENTRATED PROXYLANE
Helps support the skin’s integrity and correct visible signs of aging, like wrinkles and laxity.

• 4.25% WILD FRUIT FLAVONOIDS
Combination of blueberry and pomegranate extracts helps reduce oxidative stress, which can be linked to A.G.E. formation, and protect against free radical damage.

• 0.1% GLYCYRRHETINIC ACID
Helps counter dull tone, which can be linked to A.G.E. accumulation, and is known for its soothing properties.

• 3% HEPES
Activates natural enzymes in the skin to promote even cell turnover while hydrating the skin.

• 1% NIACINAMIDE
Water-soluble vitamin, also known as vitamin B3, soothes and helps support the skin’s moisture barrier.

Full ingredient list

PHYSICIAN INSIGHT

"Clients are getting a heavy hitter with A.G.E. Interrupter Advanced as it is a corrective moisturizer that contains ingredients that improve the signs of aging. I love this product as it does double duty and a little goes a long way!"

Dr. Lori Shapiro MD, Thornhill Dermatology Centre, Dermatologist

FREQUENTLY ASKED QUESTIONS

Answers to Your Frequently Asked A.G.E. Interrupter Advanced Questions

How does A.G.E. Interrupter Advanced differ from the original A.G.E. Interrupter?

Like the original A.G.E. Interrupter, A.G.E. Interrupter Advanced is a wrinkle cream that fights glycation. The new A.G.E. Interrupter Advanced includes an increased active concentration of Proxylane (+20%) and wild fruit flavonoids (+12.5%), as well as new efficacious ingredients, such as glycyrrhetinic acid. In addition to performance improvement, our product development and lab teams were able to dramatically improve the sustainability profile. The texture of A.G.E. Interrupter Advanced is similar to its predecessor, A.G.E. Interrupter, now with an optimized scent.

Why does A.G.E. Interrupter Advanced have a different color than the previous formula?

A.G.E. Interrupter Advanced features a combination of wild fruit flavonoids (blueberry and pomegranate extracts) that are 12.5% higher than the additional single flavonoid (blueberry extract) used in the original A.G.E. Interrupter formulation. These ingredients can contribute to a slightly pink tone. Further, due to color variances of these naturally-derived ingredients, this formula’s color may also vary, but will remain effective.

What does A.G.E. Interrupter Advanced do?

Can I use A.G.E. Interrupter Advanced with retinol?

Does A.G.E. Interrupter Advanced cream get rid of wrinkles?

What is glycation?

CLINICALLY PROVEN RESULTS

In a 12-week study, A.G.E. Interrupter Advanced reduced global fine lines by -14.1% and targeted deep wrinkles by -7.9%.

A.G.E. Interrupter Advanced improved attributes associated with skin aging and glycation, including lines and deep wrinkles in multiple facial zones:

+30%		Skin density
-14%		Global fine lines
-11.5%		Forehead wrinkles
-11.2%		Nasolabial folds
-7.3%		Glabellar wrinkles
-7%		Crow's feet

See Protocol

Protocol: A 12-week, single-center, clinical study was conducted on 77 females with Fitzpatrick type I-VI, ages 38-70, and mild to moderate global wrinkles, fine lines, laxity, rough skin texture, uneven skin tone, and a dull complexion. A.G.E Interrupter Advanced was used twice daily over face, neck and chest in conjunction of a sunscreen for 12 weeks. Efficacy and tolerance evaluations were conducted at baseline, weeks 4, 8, and 12.

HOW DOES GLYCATION AGE YOUR SKIN?

An accumulation of the body's natural sugars can damage skin during a reaction called glycation. In this process, sugars bind to the proteins responsible for keeping skin supple, soft and youthful-looking, like collagen and elastin. This forms harmful molecules known as Advanced Glycation End-Products (A.G.E.), which cause protein damage and lead to visible wrinkles, loss of firmness and aging skin.